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Microsampling Supports Pediatric Study at Semmelweis University

August 2023 — Clinical researchers at Semmelweis University in Hungary announced they will use Mitra® microsampling devices donated by Trajan Scientific and Medical (Trajan) to conduct a neonate research study.

Newborn baby, neonateThe Neonatal Intensive Care Unit of the Pediatric Center of Semmelweis University received 200 Mitra devices donated through Trajan's Microsampling Research Support Program.

The donated Mitra devices enable the researchers to evaluate new sampling methods and develop less invasive blood tests for newborn and premature babies.

The Mitra device is based on volumetric absorptive microsampling, which absorbs a micro-volume blood sample of just 10, 20, or 30 µL. Mitra devices are based on patented VAMS® technology.

newborn sample collection, heel stickThe objective of the Pediatric Center’s study is to identify a precise, reliable, and gentle sampling method that requires less blood sample volume for steroid hormone analysis in neonates.

A newborn baby has only about 80 ml of blood per kilogram of body weight, so it is important to minimize the amount of blood taken from them for testing to avoid a negative impact on their health and well-being. The Mitra device collects microsamples that are less than one-tenth of the blood sample size required for standard laboratory measurements.

“In terms of laboratory measurements of newborns and premature babies, this quantitative difference is significant, since compared to their total blood volume, the amount of blood required for laboratory tests already represents a significant loss,” said Dr. Kata Kovács, assistant lecturer at the Pediatric Center.

Mitra device in LabDr. Kovács reported that their clinical research team aims to validate the 10 µL Mitra microsamplers under the leadership of professor Miklós Szabó.

The studies will compare steroid levels from capillary blood samples (10 microliters) and standard arterial blood samples (200 microliters) to facilitate clinical application of the new sampling method. The donated devices from Trajan have made implementation of the two-year research plan possible. 

The technical expertise for the study is provided by the Laboratory of Mass Spectrometry and Separation Technology, Department of Laboratory Medicine, Semmelweis University.

About the Pediatric Center of Semmelweis University

Semmelweis University LogoSemmelweis University is a leading institution of higher education in Hungary and the Central European region within the area of medicine and health sciences. Its main commitment is based on the integrity of education, research, and healing, which make Semmelweis University an internationally renowned center of knowledge. Research, development, and innovation comprise an important part of the University’s three-fold mission. Its research targets are early diagnostics and therapy, disease prevention and active ageing. The Department of Pediatrics (Bókay Street Unit), Semmelweis University has a 181-year history. It has been led by Dr. Attila Szabó since October 2013. For more information, please visit www.semmelweis.hu.

About Neoteryx, Microsampling Solutions by Trajan

Neoteryx, a world leader in microsampling devices, was acquired by Trajan in 2021. Today, Trajan’s full line of microsampling solutions carry the Neoteryx brand. The Neoteryx range of microsampling products provide precise, quantitative remote specimen collection. They are easy to use, virtually painless, and amenable to automated analysis in the lab, easing workflows and enabling decentralized research and healthcare models. The product portfolio includes the Mitra® device based on VAMS® technology and the hemaPEN® that advances both capillary and dried blood spot (DBS) technologies, with more microsampling products in the pipeline. For more information on microsampling solutions, visit www.neoteryx.com.

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Media Contacts:

Semmelweis University: press@semmelweis.hu

Trajan: Amy Miller, WE Communications, amymi@we-worldwide.com

Find out how scientists apply remote microsampling in decentralized research & pediatric studies around the globe.

In some territories our devices are supplied for therapeutic or IVD use Outside of those territories our devices are supplied for research use only

Image Credits: Trajan, Neoteryx, iStock, Semmelweis University

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