GenTegraRNA-NEO for Microsampling (RUO)
Did you know that RNA can remain stable in a blood sample stored for more than 3 days at room temperature? With the GenTegraRNA-NEO solution, an Active Chemical Protection™ (ACP) technology by GenTegra supplied by Trajan for use on Mitra® blood microsampling devices, this is now possible! The protection solution arrives as a lyophilized powder that you rehydrate in the lab. It can be applied to VAMS® tips on Mitra® devices to stabilize and preserve RNA at ambient temperatures for 7 days prior to extraction for your research applications.
Treat Microsampling Devices
GenTegraRNA-NEO arrives in your research lab as a dry matrix in a tube. Follow the steps outlined in the GenTegra User Guide to treat the VAMS® tips of the Mitra® devices with the rehydrated GenTegraRNA-NEO solution.
When the matrix in the tube is rehydrated, there is sufficient volume to treat 32 VAMS tips, or 8 Mitra devices (4 microsamplers in each device).
You can use the Mitra 96-Autorack™ with 4 tubes of GenTegraRNA-NEO solution to treat 96 Mitra devices in a standard 96 well conical bottom microplate. The treated Mitra devices can be used exactly as you would the untreated Mitra devices.
Benefits for your research applications include:
Quantitative RNA recovery (0.125-0.150 ng) High-quality RNA (3.0-8.0 RIN) Easily store & ship treated Mitra devices RNA-stable for 7 days at ambient temps
Compatible Applications: tRNA extraction from blood mRNA, miRNA from blood
Finger-Stick Microsampling for RNA Studies
Researchers can offer Mitra® devices that have been pre-treated with the GenTegraRNA-NEO solution to collect blood microsamples for a range of RNA studies. The treated devices can be used to sample cohorts onsite or remotely with ease.
The GenTegraRNA-NEO solution is typically paired with a 4-sampler Mitra device format featuring 30 µL VAMS tips. The devices arrive in a protective plastic housing that has barcoding for chain of custody.
4 x 30 µL blood samples Minimally invasive method Easy to use for a variety of cohorts Sample collection for RNA research Barcoding to manage chain of custody
Samples Remain RNA-Stable for 7 Days
The treated Mitra devices overcome some of the common challenges associated with RNA research, providing benefits that include:
RNA-stable w/out cold shipping or storage Remote sampling w/out trained staff Access to diverse & underserved populations Rapid processing using 96 well-plates Manual processing using standard tubes Quality samples generate reliable data Compatible with standard DBS workflowsDownload the GenTegraRNA-NEO User Guide!
Add Active Chemical Protection™ of RNA to VAMS® Tips on Mitra® Devices
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