Those at work and innovating in the realms of clinical trials, drug development, and pharma face the largest challenges of their careers. But they do so armed with some of the finest medical tools ever known to man, empowered by opportunities never imagined before.
A microsampling pioneer in Italy has recently developed, validated, and submitted for publication a new LC-MS/MS method for measuring concentrations of a range of antiepileptic drugs (AEDs) using Volumetric Absorptive Microsampling (VAMS™) technology. Dr. Ugo de Grazia and his collaborators at Fondazione IRCCS Istituto Neurologico Carlo Besta Neurological Hospital in Milano have established a useful example for facilitating easier antiepileptic drug monitoring and for dealing extraction difficulties of small drugs on different physical-chemical properties.
Patient monitoring is always an important part of the medical process, but it’s particularly crucial when patients are using drugs with a narrow therapeutic index. Drugs with a narrow therapeutic index are drugs in which the dosage must be exact; otherwise, it could lead to serious negative reactions, failures, or dependency. Regular therapeutic drug monitoring is very important for patients taking these drugs.
The Mitra® microsampling device, based on Volumetric Absorptive Microsampling (VAMS™) technology developed by Neoteryx, is a simple instrument. It collects small, volumetrically accurate specimens of blood (and other biological fluids) and allows for remote sampling, taking blood collection out of the clinic.
Topics: Smarter Healthcare
There are many cases in which it is necessary to test people for alcohol consumption, including organ transplants, driver’s license regranting, and more. Traditional testing methods involving hair or urine have obvious and subtle drawbacks, and traditional alcohol biomarkers can't always be used to make finer distinctions between teetotalers, social drinkers, and heavy drinkers or alcoholics.
Over the past few years, the field of medicine has witnessed advancements that have brought new convenience, comfort, and efficiency to patient treatment. One of these is microsampling.