Share this
Revolutionizing PFAS Detection with Mitra VAMS Technology
by Neoteryx Microsampling on February 27,2025
PFAS contamination has become a major public health concern, with these persistent chemicals accumulating in the human body through exposure to contaminated water, food, and consumer products.Accurate biomonitoring is essential to assess exposure levels and potential health risks, yet traditional methods rely on venous blood collection, requiring trained personnel, specialized laboratories, and complex cold-chain logistics.
To overcome these challenges, researchers from Michigan State University, Duke University, the Colorado School of Mines, Eurofins Environment Testing Northern California LLC, and Phenomenex Inc. have evaluated the use of Mitra® Volumetric Absorptive Microsampling (VAMS®) technology, for PFAS quantification in human blood and serum.
Their findings highlight Mitra with VAMS technology as a promising alternative, offering standardized sample collection with a fixed 30 µL blood volume while eliminating the logistical difficulties of traditional blood collection.
Using the SCIEX® 7500 system, the study demonstrated that VAMS achieves detection limits as low as 0.1 to 1.0 ng/mL, making it suitable for PFAS biomonitoring in the general population.
Comparisons with National Institute of Standards and Technology (NIST®) SRM 1957 human serum samples confirmed that VAMS provides accuracy comparable to traditional serum-based techniques while improving efficiency in PFAS extraction and analysis.
Additionally, VAMS offers advantages such as reduced sample volume requirements, simplified storage and transport without dry ice, and accessibility in remote or resource-limited settings. These benefits make it an attractive option for large-scale studies, occupational exposure monitoring, and clinical research into PFAS-related health effects.
The ability to reliably detect PFAS in blood and serum is crucial for understanding the long-term impact of these contaminants on human health. PFAS exposure has been linked to endocrine disruption, immune system impairment, developmental toxicity, and an increased risk of certain cancers.
By offering a more practical and efficient alternative to traditional blood collection, VAMS technology enhances exposure assessment and supports regulatory decision-making. This innovation empowers researchers and public health officials with the tools needed to better monitor PFAS exposure, inform mitigation strategies, and ultimately safeguard human health.
Share this
- Microsampling (41)
- Mitra® Device (34)
- Industry News, Microsampling News (33)
- Company Press Release, Product Press Release (21)
- Research, Remote Research (18)
- Infectious Disease, Vaccines, COVID-19 (15)
- Clinical Trials, Clinical Research (14)
- Biomonitoring, Health, Wellness (10)
- Blood Microsampling, Serology (10)
- Decentralized Clinical Trial (DCT) (8)
- Omics, Multi-Omics (7)
- Venipuncture Alternative (6)
- Skin Microsampling, Microbiopsy (5)
- Harpera Device (3)
- Specimen Collection (3)
- Toxicology, Doping, Drug/Alcohol Monitoring, PEth (3)
- Pharmaceuticals, Drug Development (2)
- Therapeutic Drug Monitoring, TDM (2)
- Antibodies, MAbs (1)
- Environmental Toxins, Exposures (1)
- Preclinical Research, Animal Studies (1)
- hemaPEN® Device (1)
- February 2025 (4)
- September 2024 (1)
- August 2024 (1)
- May 2024 (2)
- January 2024 (1)
- December 2023 (2)
- November 2023 (3)
- October 2023 (2)
- September 2023 (1)
- August 2023 (3)
- July 2023 (3)
- June 2023 (1)
- May 2023 (2)
- April 2023 (1)
- March 2023 (2)
- February 2023 (1)
- January 2023 (2)
- December 2022 (1)
- November 2022 (1)
- October 2022 (2)
- August 2022 (1)
- April 2022 (1)
- February 2022 (1)
- January 2022 (1)
- December 2021 (1)
- November 2021 (1)
- October 2021 (2)
- September 2021 (1)
- August 2021 (2)
- July 2021 (2)
- June 2021 (2)
- April 2021 (1)
- March 2021 (2)
- February 2021 (1)
- January 2021 (1)
- December 2020 (1)
- November 2020 (1)
- October 2020 (1)
- September 2020 (2)
- August 2020 (3)
- July 2020 (3)
- June 2020 (2)
- May 2020 (1)
- April 2020 (3)
- October 2019 (1)
- March 2019 (1)
- January 2019 (1)
- November 2018 (1)
- August 2018 (1)
- July 2018 (1)
- June 2017 (1)
- April 2017 (1)
- March 2017 (1)
- February 2017 (1)
- May 2016 (1)
- December 2015 (1)
- October 2015 (1)
- August 2015 (1)
- August 2014 (1)
- July 2014 (1)
No Comments Yet
Let us know what you think