the microsampling blog

In the US, use of the Mitra device is limited to research and non-diagnostic applications. In many countries outside the US, the Mitra device can be used as a sample collection device for clinical diagnostic applications, as referenced in some content.

how children experience venipuncture

by Neoteryx | 2 min read

shutterstock_296219954.jpgImagine that you're four or five years old. Do you remember the perspective from which you viewed the world? Everything was bigger than you were, especially the things that frightened you, like locomotives, planes, clowns and elephants. You were little and easily frightened.

One of your worst fears was pain. Some pain you accepted as the price of having fun. Running, jumping, climbing trees and roller skating all involved pain when you fell down. Unless the injury was worse than usual (or your Mom was nearby), you'd just pick yourself up and go back to playing.

Other pains were much worse and more frightening, especially anything involving needles. Getting shots was terrible, but having blood drawn ranked right up there with gunshot wounds as far as you were concerned. Not that you ever thought of it in those terms.

Children feel pain just as adults do, but their brains are different in both anatomy and neurochemistry. A recent study done by scanning the brains of infants and adults with an MRI indicates that children may feel pain more intensely than adults. They certainly have a very different emotional reaction to pain than adults do.

Drawing blood on a young child can be difficult for everyone: the child, the parents and the laboratory technician. Children have a layer of subcutaneous fat that is protective from both injury and famine. But that fat buries their veins very effectively. Not until puberty do the veins start to be well defined. Before that, finding a vein requires at least a couple of minutes with a tourniquet tied tightly around the arm and some probing with a needle.

The whole experience is not only painful, but terrifying to the child, who has no idea why he or she is being attacked in this way. Sometimes the child has to be restrained in order to obtain the blood, which causes further trauma.

Microsampling is another way of collecting blood samples that doesn't involve drawing from a vein. Its pediatric applications are just beginning to be explored.


The blood is obtained from a single drop from a fingerstick, withdrawing far less blood from the child and far less painfully. The pain is so brief that most children don't even cry. They watch with fascination as the blood is drawn up into capillary tubes. Microsampling keeps kids calm, parents relaxed, and laboratory technicians sane.

Originally published Feb 1, 2018 4:46:00 AM, updated on October 21, 2019


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