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the microsampling blog

Mitra® Microsampling: Advancing Pre-Clinical RNA Biomarker Research

RNA-Seq-Vs-DriverMap-Profile-heatmap

Seamless Integration of Sample Collection and Comprehensive Transcriptome Profiling

Mitra® microsampling technology, now incorporated into Cellecta’s DriverMap™ RNA sequencing kits, is revolutionizing biomarker discovery by enabling efficient and scalable blood collection for pre-clinical human studies.

With precise volumetric sampling and robust RNA stabilization, Mitra allows for high-resolution, reproducible transcriptome profiling, resulting in minimal variability and accurate outcomes.

Reliable RNA Stability for Scalable Research

GenTegraRNA-NEO™ Stabilization: This technology ensures RNA integrity even during extended storage.

Remote Collection Capabilities: Mitra enables remote sample collection and centralized processing, simplifying multi-site pre-clinical studies.

Seamless Compatibility with Cellecta’s DriverMap™ Genome-Wide Targeted RNA-Seq Kit

High-Sensitivity Gene Expression Analysis: The technology works effectively with the DriverMap™ targeted RNA sequencing system, allowing for accurate detection of differential gene expression changes in small blood volume samples, which is crucial for drug discovery and disease research.


Simplifying Blood Collection for High-Throughput Targeted RNA Sequencing

Standardized Process: Mitra microsampling offers a consistent and user-friendly blood collection method across multiple sites.

Reduced Logistical Challenges: The system facilitates remote and decentralized sampling, making large-scale sample collection more feasible.


Proven Performance in Human RNA Transcriptome Profiling Studies

There is over **90% overlap** in gene expression profiles between Mitra microsamples and standard whole blood (Tempus™ tubes).A strong correlation (r = 0.94) exists between gene expression results from Mitra samples and those obtained from traditional blood collection methods.


Advancing Biomarker Discovery in Immunotherapy and Beyond

Mitra-powered DriverMap™ targeted RNA-sequencing technology supports high-resolution biomarker discovery in areas such as cancer, infectious diseases, and drug response studies.
It effectively detects differentially expressed genes (DEGs) in both stimulated and unstimulated blood samples.


Microsamplers and Stabilizers needed for each Cellecta Driver Map Configuration:

Learn more about Driver Map Genome-Wide Targeted RNA-Seq kits.

No. Individual/Rxn Kits

Mitra Tips + GTR-NEO RNA Stabilizer

Driver Map Configuration


6

Qty 1 VM-302SNLR | Mitra 30ul 2 sampler Device 30/PK RUO 


Qty 1 GTRNEO-32 | GenTegra GTR-NEO Active Chemical Protection of RNA, 2mL Tube

24 rxn 

 


12
 

24

Qty 3 VM-302SNLR Mitra 30ul 2 sampler Device 30/PK RUO


Qty 3 GTRNEO-32 | GenTegra GTR-NEO Active Chemical Protection of RNA, 2mL Tube

96 rxn


48

 

To Request a Quote or for More Information on Driver Map kits Please Submit your Contact Details Below. 

 

 

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