Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This clinical validation study compared VAMS with conventional blood matrices for dasatinib and imatinib therapeutic drug monitoring. VAMS was a viable alternative for imatinib and may support longitudinal dasatinib monitoring, providing a foundation for future patient-collected home samples.
This clinical study evaluated VAMS conversion methods for therapeutic monitoring of oral targeted anticancer drugs and their metabolites in 153 patients. Seven of ten analytes met the acceptance criteria, patients responded positively to home sampling, and the authors recommended independent validation before routine use.
Researchers developed and clinically validated a VAMS–LC-MS/MS method for measuring mycophenolic acid and its glucuronide metabolite in kidney transplant recipients. Corrected microsample results closely agreed with plasma measurements, remained stable for three months at room temperature, and supported patient self-sampling.
This study compared self- and professionally collected VAMS capillary blood and saliva with venous serum for SARS-CoV-2 antibody testing. Capillary-blood results showed excellent agreement and positive user experience, while the authors noted that additional self-sampling training may improve reliability.
Researchers developed and validated a simple Mitra VAMS–HPLC-UV method for fluconazole in 10 µL blood samples from pediatric transplant patients. More than 200 clinical samples were successfully analyzed, supporting a lower-cost approach to therapeutic monitoring.
Researchers developed a rapid LC-MS/MS method for three cystic-fibrosis medicines in plasma, dried plasma spots, and VAMS whole blood. Plasma and dried-plasma results were interchangeable, while hematocrit-based correction was needed to estimate plasma-equivalent concentrations from VAMS.
Researchers integrated epidemiological and genetic data from longitudinal school surveillance to model how SARS-CoV-2 transmission changed across variant periods. Rising community-acquired infection progressively reduced the potential impact of school-based interventions, supporting strategies that adapt to the broader epidemiological context.
This study analytically and clinically validated LC-MS/MS measurement of everolimus in venous blood, Mitra VAMS, and Capitainer microsamples from adult transplant recipients. Both microsampling devices agreed well with the venous reference and showed negligible hematocrit effects, supporting decentralized therapeutic monitoring.
Researchers compared global metabolomic profiles from Mitra, Capitainer, Whatman-card, and conventional plasma samples. Mitra and Capitainer provided rich and often precise metabolic information, although device-specific and metabolite-specific differences require evaluation for each application.
This study validated Mitra at-home sampling for large-scale measurement of anti-SARS-CoV-2 antibodies. Capillary VAMS results correlated strongly with venous serum and remained stable for months at room temperature, supporting community surveillance and vaccine studies.
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