Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This study examines quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting. These study results demonstrate the feasibility of quantitating BCAAs and BCKAs reliably with PCS devices, with high acceptability from study participants.
This study examines practical application of blood microsampling, with a focus on an effective vams-based workflow for anabolic androgenic steroid analysis. The study provides a validated, cost-effective alternative to traditional sampling methods, confirming that VAMS is a promising minimally invasive tool for steroid detection in whole blood and highlighting its potential for broader applications in translational chemistry and personalised medicine.
This study examines high sensitivity mass spectrometry for multiple myeloma monitoring using microsampling, with a focus on a patient-centered approach. Participants provided meaningful suggestions to the study design based on their lived experience and emphasized the importance of making the patient-facing documents more concise and accessible.
This work describes the development of a dried plasma spot method to enhance the stability of tyrosine kinase inhibitors for therapeutic drug monitoring: a comparative study with wet plasma. DPS demonstrated improved stability and provided concentration measurements comparable to plasma for selected TKIs, suggesting its potential for application in TDM.
This study examines deep insights into microsampling technologies for global lipidomic profiling of human whole blood using high-throughput LC-MS. Precision analysis of deuterated lipid species and the 195 endogenous lipids indicated that qDBS and VAMS had higher precision compared to DBS.
This study compared microsampling devices, extraction solvents, and derivatization protocols for detecting 27 steroid esters in dried blood. Mitra tips produced high extraction efficiency with minimal matrix effects, while the optimal derivatization approach varied by steroid ester.
This study evaluates a microsampling approach for measuring localized inflammation through small volumes of leaking amniotic fluid. The findings provide preliminary support for a less invasive alternative to amniocentesis when assessing intrapartum inflammation.
This feasibility study assessed surrogate-matrix calibrators for ligand-binding analysis of VAMS and Tasso-M20 dried blood samples. The selected surrogate matrix supported accurate quantification and dilution of high-concentration samples, reducing the need to prepare daily wet-blood calibrators.
Researchers compared Leishmania major distribution and transmission potential in a natural reservoir host and a laboratory mouse model. Microbiopsy-based assessment showed heterogeneous parasite distribution and substantial host-model differences in the parasite burden associated with sand-fly infection.
A human intervention study used Mitra VAMS capillary samples, urine, and feces to characterize the toxicokinetics of citrinin. Population modeling generated human toxicokinetic parameters and supported the adequacy of the current uncertainty factor used to address inter-individual variability.
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