Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This pharmacokinetic study compared traditional venipuncture with self-collected blood microsamples for measuring centanafadine. The validated microsampling method showed concordance with venous sampling and supported feasibility of at-home PK sample collection.
This nationwide Belgian survey used at-home VAMS to assess thiamine biomarker status in adults. The study found that biomarker results identified thiamine insufficiency not apparent from intake data, supporting VAMS for large-scale nutritional assessment.
This study evaluated conductive vial electromembrane extraction as a cleanup method for pharmaceuticals collected on VAMS tips. The optimized workflow improved reproducibility and reduced matrix effects, supporting potential use in routine bioanalytical applications.
This thesis examines expanding the detection of anabolic steroid doping, with a focus on alternative sample matrices and techniques. All four laboratories were able to detect the spiked testosterone esters in both serum and DBS samples, demonstrating their capabilities for the analysis of these substances and supporting the strategies for a harmonised approach.
This thesis examines environmental exposure to metals in children and their effects on autism spectrum disorder. Together, these studies provide a comprehensive understanding of how environmental exposures, spatial disparities, and community engagement intersect to influence ASD outcomes in Alabama.
This study examines wide-targeted metabolomics in dried blood spots. Stability testing confirmed that most metabolites remain reliable in DBS samples stored at room temperature for up to three weeks.
This study examines volumetric absorptive microsampling for in vitro metabolism of the recent synthetic cannabinoid receptor agonist 5F-PB-22.
This work examines the use of blood micro-samples in forensic thanatology. Heroin, several benzodiazepines, and cocaine showed excellent stability on DBS, while they degraded or disappeared in conventional tubes.
This study examines toward minimally invasive metabolomics, with a focus on GC-MS metabolic fingerprints of dried blood microsamples in comparison to plasma. Overall, the results suggest that BmuS is a viable alternative for untargeted blood metabolomics, providing comparable information.
This study examines recent trends in microsampling and reduced-volume sample preparation procedures. Techniques such as Solid-Phase Microextraction (SPME) and Volumetric Absorptive Microsampling (VAMS) are being explored as promising tools for obtaining dried biological matrices, such as blood, urine, and saliva offering potential improvements over traditional methods like Dried Blood Spotting (DBS).
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