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Microsampling Publications Library

Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.  

Search results are matched to the publication record, including title, abstract, keywords, authors, and other indexed details. All search terms must appear in the record for it to be included in your results.

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Showing 8 publications on page 59.

Volumetric absorptive microsampling: a dried sample collection technique for quantitative bioanalysis

Denniff, P.; Spooner, N.
Anal Chem | 2014

This article evaluates VAMS as a quantitative dried-blood collection technique designed to reduce volume and homogeneity biases associated with punched DBS samples. Stress testing informed practical recommendations for reliable sample collection and handling.

Microbiopsy engineered for minimally invasive and suture-free sub-millimetre skin sampling

Lin, L. L.; Prow, T. W.; Raphael, A. P.; Harrold Iii, R. L.; Primiero, C. A.; Ansaldo, A. B.; Soyer, H. P.
F1000Res | 2013

This engineering study describes a submillimetre, suture-free skin microbiopsy designed for molecular diagnosis and research. Volunteer testing showed rapid closure of the small sampling site and recovery of DNA and RNA quantities suitable for downstream analysis.

Effects of ex vivo skin microbiopsy on histopathologic diagnosis in melanocytic skin lesions

Banan, P.; Lin, L. L.; Lambie, D.; Prow, T.; Soyer, H. P.
JAMA Dermatol | 2013

This study evaluated whether ex vivo microbiopsy artifacts interfere with histopathologic diagnosis of melanocytic skin lesions. Across five lesions, the small defects did not hamper diagnosis, supporting microbiopsy for molecular sampling before conventional assessment.

The opportunity for microbiopsies for skin cancer

Prow, T. W.; Lin, L. L.; Soyer, H. P.
Future Oncol | 2013

This perspective describes how minimally invasive skin microbiopsy could support molecular profiling and personalized dermato-oncology by enabling biomarker assessment across heterogeneous skin lesions.

A plea for biobanking of all equivocal melanocytic proliferations

Soyer, H. P.; Lin, L. L.; Prow, T. W.
JAMA Dermatol | 2013

This article argues for biobanking equivocal melanocytic lesions to support combined morphologic and molecular evaluation. It discusses minimally invasive skin microbiopsy as a way to obtain nucleic acids for research while limiting damage to the lesion.

Current and future use of "dried blood spot" analyses in clinical chemistry

Lehmann, S.; Delaby, C.; Vialaret, J.; Ducos, J.; Hirtz, C.
Clin Chem Lab Med | 2013

This review examines the established and emerging use of dried blood spot analysis in clinical chemistry. It summarizes the range of measurable analytes, current barriers to routine adoption, and opportunities created by newer analytical technologies such as mass spectrometry.

Programming pluripotent precursor cells derived from Xenopus embryos to generate specific tissues and organs

Borchers, A.; Pieler, T.
Genes (Basel) | 2010

This review describes how pluripotent cells from Xenopus embryos can be directed to form specific tissues and organs. Conserved developmental signaling pathways have enabled experimental generation of structures including pancreas, liver, kidney, eye, and heart, informing future regenerative-medicine research.

Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS

Matuszewski, B. K.; Constanzer, M. L.; Chavez-Eng, C. M.
Anal Chem | 2003

This article examines strategies for assessing and controlling matrix effects in quantitative HPLC-MS/MS bioanalysis. Comparative testing showed that interface selection can materially affect ion suppression, underscoring the need for matrix-effect evaluation during method development.

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