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Microsampling Publications Library

Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.  

Search results are matched to the publication record, including title, abstract, keywords, authors, and other indexed details. All search terms must appear in the record for it to be included in your results.

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LC-MS/MS and volumetric absorptive microsampling for quantitative bioanalysis of cathinone analogues in dried urine, plasma and oral fluid samples

Mercolini, L.; Protti, M.; Catapano, M. C.; Rudge, J.; Sberna, A. E.
J Pharm Biomed Anal | 2016

This study developed and validated a VAMS–LC-MS/MS method for six synthetic cathinones in dried urine, plasma, and oral fluid. Successful application to samples from users supports future use of the microsampling approach in forensic and sports drug-testing settings.

Stable-Isotope Dilution HPLC-Electrospray Ionization Tandem Mass Spectrometry Method for Quantifying Hydroxyurea in Dried Blood Samples

Marahatta, A.; Megaraj, V.; McGann, P. T.; Ware, R. E.; Setchell, K. D.
Clin Chem | 2016

Researchers developed an LC-MS/MS method for measuring hydroxyurea in small dried-blood samples collected on cards or VAMS devices. The assay was linear, precise, and stable, supporting minimally invasive therapeutic monitoring for patients with sickle cell anemia.

Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin

Parker, S. L.; Guerra Valero, Y. C.; Lipman, J.; Roberts, J. A.; Wallis, S. C.
Bioanalysis | 2016

This study examined whether extraction recovery for vancomycin changes with drying time in dried plasma spots and VAMS. The work highlights the importance of harmonizing drying protocols between calibrators, controls, and clinical samples to protect quantitative accuracy.

Determination of ultra-trace amounts of prosthesis-related metals in whole blood using volumetric absorptive micro-sampling and tandem ICP - Mass spectrometry

Bolea-Fernandez, E.; Phan, K.; Balcaen, L.; Resano, M.; Vanhaecke, F.
Anal Chim Acta | 2016

This study combined VAMS with tandem ICP-MS to measure ultra-trace prosthesis-related metals in whole blood. Reference materials and spiked clinical samples confirmed accurate, sensitive measurement across the targeted elements.

Procedures for Analysis of Dried Plasma Using Microsampling Devices to Detect Sulfur Mustard-Albumin Adducts for Verification of Poisoning

John, H.; Willoh, S.; Hormann, P.; Siegert, M.; Vondran, A.; Thiermann, H.
Anal Chem | 2016

This study developed dried-plasma microsampling procedures to detect sulfur mustard–albumin adducts as evidence of poisoning. The methods produced reliable samples that were less constrained by shipping and handling requirements.

Novel Microsampling Technique with Mitra in Analysis of Perfluoroalkyl Acids in Blood

National Institute for Health and Welfare
2015

This presentation evaluates Mitra microsampling for measuring perfluoroalkyl acids in blood. The workflow provides efficient extraction and supports practical collection of real-world samples.

Evaluation of the Mitra microsampling device for dry sample processing in a pharmacokinetic/pharmacodynamic study of beta-lactams

Karin kipper
2015

This study evaluates Mitra microsampling for dried-sample processing in a pharmacokinetic and pharmacodynamic investigation of beta-lactam antibiotics. The approach was assessed as a lower-volume alternative for studying drug exposure in critically ill patients.

Enhanced Stability of Dried Haematic samples for new psychotropic synthetic compound monitoring

Unibo
2015

This presentation evaluates dried-sample microsampling for monitoring new synthetic psychotropic compounds. The proposed workflow combines improved analyte stability with a fast, economical analytical approach.

Comparison of Blood Microsampling Techniques for Discovery PK Studies in Rats: Capillary Microsampling (CMS) and a Dried Matrix Microsampling Device

Sanofi
2015

This study compares blood microsampling techniques for discovery PK studies in rats: capillary microsampling (CMS) and a dried matrix microsampling device. Both procedures were based on rat tail vein sampling and were found to work well for rat discovery PK sampling.

Application of Microsampling Techniques for Detection of Anti-drug Antibody (ADA) in Rat

Biogen
2015

This study applies microsampling techniques for detection of anti-drug antibody (ADA) in rat. Raw signal comparison of three collection methods showed that samples with high levels of ADA in serum also measured high using DBS and Mitra.

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