Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
Researchers validated a VAMS-based LC-MS/MS method for measuring doxycycline in urine to monitor malaria chemoprophylaxis adherence. Results agreed with directly diluted samples, supporting VAMS as a practical field alternative for compliance assessment.
This study evaluated dried capillary VAMS samples for IGF-1 measurement using an automated chemiluminescent immunoassay. The approach was feasible, but lower values at high serum concentrations indicate that dedicated dried-blood reference ranges require further study.
This season-long study combined proteomic profiling with athlete-reported illness and training-distress measures in university swimmers. Immune-protein patterns helped distinguish the most stressful training periods, while athlete reports did not consistently align with coaches’ assessments.
This proof-of-concept study compared VAMS capillary-blood cannabidiol measurements with conventional plasma results in patients with epilepsy. Concentrations were strongly correlated, supporting VAMS as a minimally invasive tool for personalized therapeutic monitoring.
This review considers VAMS as an alternative sampling method for clinical trials and therapeutic drug monitoring during the COVID-19 pandemic. It highlights home collection, fixed-volume sampling, room-temperature shipment, low sample volume, and reduced hematocrit effects as practical advantages.
This clinical comparison assessed VAMS, dried blood spot, and conventional venous sampling for tacrolimus trough monitoring in kidney-transplant patients. Dried blood spots showed stronger agreement with venous blood, while VAMS had more sample-quality problems and was not considered an equivalent replacement under the study conditions.
This study developed and validated a VAMS–UHPLC-MS/MS method for gamma-hydroxybutyric acid in human blood. The assay met current validation guidelines and produced results comparable with a plasma-based method in a proof-of-concept patient sample.
This study developed and validated an LC-MS/MS method for selumetinib in VAMS whole-blood samples. All validation criteria were met, and the drug remained stable under both ambient and frozen storage conditions.
This study evaluated a single workflow for measuring 14 drugs in dried blood using whole-blood and serum calibrators. Multiplexed testing was feasible, but performance varied by analyte and requires confirmation with clinical specimens.
This study developed and clinically validated a VAMS method for 14 antidepressants, antipsychotics, and active metabolites. Derived blood-to-plasma conversion factors supported use of the workflow in routine health care.
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