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Microsampling Publications Library

Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.  

Search results are matched to the publication record, including title, abstract, keywords, authors, and other indexed details. All search terms must appear in the record for it to be included in your results.

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Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol

Mc Laughlin, A. M.; Schmulenson, E.; Teplytska, O.; Zimmermann, S.; Opitz, P.; Groenland, S. L.; Huitema, A. D. R.; Steeghs, N.; Muller, L.; Fuxius, S.; Illerhaus, G.; Joerger, M.; Mayer, F.; Fuhr, U.; Holdenrieder, S.; Hempel, G.; Scherf-Clavel, O.; Jaehde, U.; Kloft, C.; For The On-Target Study, Consortium
Cancers (Basel) | 2021

This protocol describes the ON-TARGET study, which evaluates routine therapeutic drug monitoring for targeted oral anticancer drugs. It also tests VAMS collection as a step toward a nationwide, home-compatible monitoring infrastructure.

Evidence for deficits in behavioural and physiological responses in aged mice relevant to the psychiatric symptom of apathy

Jackson, M. G.; Lightman, S. L.; Gilmour, G.; Marston, H.; Robinson, E. S. J.
Brain Neurosci Adv | 2021

This study examined behavioral and physiological features of apathy in aged male mice. Changes in motivation, reward sensitivity, and emotional reactivity supported the model’s potential for preclinical apathy research.

Evaluation of qPCR on blood and skin microbiopsies, peripheral blood buffy coat smear, and urine antigen ELISA for diagnosis and test of cure for visceral leishmaniasis in HIV-coinfected patients in India: a prospective cohort study

Owen, S. I.; Burza, S.; Kumar, S.; Verma, N.; Mahajan, R.; Harshana, A.; Pandey, K.; Cloots, K.; Adams, E.; Das, P.
BMJ Open | 2021

This prospective protocol evaluates minimally invasive blood, skin, and urine tests for diagnosing and confirming cure of visceral leishmaniasis in people with HIV. The study is designed to assess alternatives to invasive splenic or bone-marrow sampling.

TELEmedicine for EPIlepsy Care (TELE-EPIC): protocol of a randomised, open controlled non-inferiority clinical trial

Licchetta, L.; Trivisano, M.; Baldin, E.; Mohamed, S.; Raschi, E.; Mostacci, B.; Zenesini, C.; Contin, M.; Vigevano, F.; Bisulli, F.; Tinuper, P.; Vignatelli, L.
BMJ Open | 2021

This protocol evaluates telemedicine versus usual epilepsy care and includes VAMS finger-prick sampling for anti-seizure medication measurement. The study will compare VAMS with plasma and assess nurse-collected versus self-collected samples.

Assessment of low volume sampling technologies: utility in nonclinical and clinical studies

Williams, K. J.; Lutman, J.; McCaughey, C.; Fischer, S. K.
Bioanalysis | 2021

This study evaluated several low-volume blood-sampling technologies in nonclinical and clinical settings. The findings demonstrate feasibility while identifying practical considerations that should guide implementation and comparison with venipuncture.

Lessons learned from the COVID-19 pandemic and its impact on bioanalysis and drug development

Wickremsinhe, E. R.; Brockus, C. L.; Murphy, A. T.
Bioanalysis | 2021

This article reviews the operational impact of the COVID-19 pandemic on bioanalysis and drug development. It highlights how rapid process changes, collaboration, and removal of longstanding barriers enabled continued study support and accelerated pandemic-related work.

Volumetric absorptive microsampling: its use in COVID-19 research and testing

Rudge, J.; Kushon, S.
Bioanalysis | 2021

This review summarizes the use of VAMS in COVID-19 research, antibody testing, and remote sample collection. The published evidence supports VAMS as an effective alternative when conventional phlebotomy is impractical.

Adaptation of Elecsys((R)) anti-severe acute respiratory syndrome coronavirus-2 immunoassay to dried blood spots: proof of concept

Marchand, A.; Roulland, I.; Semence, F.; Ericsson, M.
Bioanalysis | 2021

This proof-of-concept study adapted an automated anti-SARS-CoV-2 immunoassay for volumetric dried-blood samples. Results supported dried microsamples as a practical alternative to serum or plasma for antibody testing.

Whole blood stability evaluation of monoclonal antibody therapeutics using volumetric absorptive microsampling

Li, H.; Myzithras, M.; Bolella, E.; Leonard, A.; Ahlberg, J.
Bioanalysis | 2021

This study evaluated whole-blood stability of daclizumab and trastuzumab on VAMS devices. The findings help define handling and analysis timelines for large-scale antibody studies and remote sample collection.

Remote Fingerstick Blood Collection for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Testing

Garcia-Beltran, W. F.; Miller, T. E.; Kirkpatrick, G.; Nixon, A.; Astudillo, M. G.; Yang, D.; Mahanta, L. M.; Murali, M.; Dighe, A. S.; Lennerz, J.; Thierauf, J.; Naranbhai, V.; Iafrate, A. J.
Arch Pathol Lab Med | 2021

This study evaluated remote finger-stick blood collection for SARS-CoV-2 antibody testing with a commercial immunoassay. Dried-blood extracts showed near-identical sensitivity and specificity to serum, supporting at-home and large-scale seroprevalence testing.

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