Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This study demonstrates the volumetric accuracy, precision, sample integrity, and contained storage of the hemaPEN dried-blood sampling device. The device collects four replicate 2.74 µL samples from a single source.
This application note provides a workflow for purifying DNA from whole blood collected on a Mitra microsampler using the Maxwell RSC FFPE Plus DNA Kit and Maxwell RSC Instrument.
This technical brief presents chemiluminescent immunoassay methods for measuring 12 hormones from remotely collected Mitra VAMS blood samples. It discusses the feasibility of at-home microsampling for hormone monitoring and population-health research.
This proof-of-concept study used a minimally invasive microbiopsy device to measure Leishmania donovani skin parasite load in participants in India. Skin results varied with disease status and sampling site, supporting further evaluation for transmission research and post-kala-azar dermal leishmaniasis diagnosis.
This review identified and compared 13 minimally invasive methods for acquiring dermatologic biosamples. It summarizes the sample types, applications, equipment, strengths, and limitations of approaches including microbiopsy, tape stripping, suction blistering, hair sampling, and microneedle patches.
Researchers developed and validated a VAMS–LC-MS/MS method for measuring rosuvastatin in small whole-blood samples. The assay was accurate and precise, and samples remained stable for ten days at room temperature, supporting shipment after home collection.
This study developed and validated a VAMS method for measuring 24 mycotoxins in blood. Performance remained acceptable after storage, results did not miss exposed cases compared with liquid whole blood, and the approach supported biomonitoring in resource-limited settings.
This study developed and validated an LC-MS/MS assay for tacrolimus in whole blood collected with the Mitra microsampling device. The method was accurate, precise, stable under multiple storage conditions, and unaffected by hematocrit, hyperlipidemia, or nominal tip-volume variation.
Researchers compared Mitra finger-prick and venous tacrolimus measurements in 82 kidney and liver transplant recipients. Results were highly correlated, although Mitra measurements showed an average positive bias that should be considered when using the method for therapeutic monitoring.
This critical review examined dried blood spot and VAMS assays for pharmacokinetic analysis and antimicrobial therapeutic drug monitoring in children. It highlights VAMS as a lower-volume alternative to plasma sampling while emphasizing the need to establish blood-to-plasma relationships and therapeutic ranges.
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