Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This presentation reviews the opportunities and challenges of ultra-sensitive immunoassay development and validation on the Quanterix HD-X platform. Case studies include a cytokine six-plex assay using Mitra VAMS samples, along with practical considerations for sensitivity, calibration, automation, and method development.
This method validation study developed a VAMS-based LC-MS/MS approach for monitoring multiple tyrosine kinase inhibitors. The method showed stability and performance suitable for future clinical follow-up studies using capillary microsamples.
This study evaluated volumetric microsampling for remote monitoring of immunosuppressants and kidney function in kidney transplant recipients. Results support microsampling as a potential tool for decentralized post-transplant monitoring.
This presentation evaluates extraction recovery for VAMS samples under different anticoagulant and hematocrit conditions. Recovery was analyte-dependent, and the results identify areas requiring additional optimization for consistent long-term performance.
This study validates high-throughput, semiquantitative solid-phase SARS-CoV-2 serology assays in serum and dried blood spot matrices. The assay demonstrated high levels of diagnostic specificity and sensitivity (85–99% for all analytes).
This study examines undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the united states. These data indicate that there were 4.8 undiagnosed SARS-CoV-2 infections for every diagnosed case of COVID-19, and an estimated 16.8 million infections were undiagnosed by mid-July 2020 in the United States.
This study examines therapeutic drug monitoring of lamotrigine, lacosamide, and levetiracetam in dried capillary blood-determination of conversion factors for serum-based reference ranges. A simple ratio approach using the mean ratio and Passing-Bablok regression showed the best results for all 3 AEDs.
This study examines therapeutic drug monitoring of antidepressant by minimally-invasive techniques in eating disorders patients, with a focus on a clinical research report with a focus on vortioxetine. Despite the small size of the sample, by considering these preliminary data, we are confident that further studies will allow us to outline that TDM may represent a valid tool to achieve a consistent clinical efficacy of AD in patients diagnosed with ED.
This study examines self-sampling at home using volumetric absorptive microsampling, with a focus on coupling analytical evaluation to volunteers' perception in the context of a large scale study.
This study examines microsampling for monitoring gentamicin in neonates. This proof-of-concept study demonstrates that the use of microsampling for TDM by pathology services can fulfil the requirements of providing an accurate gentamicin concentration in a timely manner.
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