Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This study examines high-temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines. Together, this study also highlights the benefits of adopting high-frequency sampling protocols in profiling vaccine-elicited immune responses.
This work describes the development and validation of an HPLC-UV method for simultaneous analysis of acrylamide and glycidamide in volumetric absorptive microsampling. Objective: Acrylamide is a carcinogenic compound that can be found in commonly consumed foods and cigarette smoke.
This study examines alternative sample matrices supporting remote sample collection during the pandemic and beyond. It is anticipated that there will be a need for laboratories to support and adapt to these new trends in healthcare.
This study examines advanced microsamples, with a focus on current applications and considerations for mass spectrometry-based metabolic phenotyping pipelines. This review supports the translation of research from the ‘bench to the community’.
Researchers validated LC-MS/MS assays for giredestrant in dried whole blood collected with Mitra and Tasso-M20 devices. Both assays met validation criteria, and the work documented device-specific stability while supporting quantitative analysis with either microsampling device.
This application note lists analytes reported or considered suitable for extraction from dried whole-blood microsamples. The list is intended as an evolving technical reference rather than an exhaustive catalog.
This study established an automated workflow for quantifying tacrolimus from hemaPEN dried blood samples using the CLAM-2030 platform. The approach combines patient-centric microsampling with automated extraction and LC-MS/MS analysis.
This case series explored a submillimetre micropunch biopsy device for molecular profiling of melanocytic lesions. The minimally invasive method collected viable cells from deeper skin layers and was evaluated as a potential aid to more targeted melanoma assessment.
This pilot study measured inflammatory markers in skin samples from patients with several inflammatory skin conditions. Distinct cytokine and chemokine patterns showed potential to complement conventional histopathology in differentiating inflammatory diseases.
This protocol describes a prospective birth cohort examining clinical, environmental, microbiome, immune, and skin-barrier factors associated with atopic dermatitis in early childhood. Repeated assessments include skin microbiopsies for transcriptomic analysis to help identify accessible biomarkers and predictors of disease onset.
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