Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This thesis examines pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients ≥75 years with polypharmacy. To reduce sampling burden, the use of a micro-sampling technique in geriatric patients was also successfully demonstrated.
This presentation describes use of Mitra VAMS sampling during a therapeutic drug-monitoring program involving a switch from Prograf to Envarsus. The workflow included serial concentration measurements and reported good patient acceptance of the device.
This presentation examines microsampling strategies, with a focus on VAMS for APAP PK. We demonstrated that finger prick sampling is suitable to investigate APAP PK, except for APAP-Cys.
This presentation examines the use of microsampling in epidemiological studies, including the stability of folate vitamers in dried blood. It highlights temperature-related degradation during summer conditions and the need for improved stabilization strategies.
This study compared microsampling-derived tacrolimus area-under-the-curve measurements with values predicted from trough concentrations in solid-organ transplant recipients. The findings support microsampling AUC monitoring as a practical method for individualized dosing.
This presentation examines measurement of tacrolimus in dried blood spots, with a focus on a fully automated sample preparation and LCMS method. This study demonstrated the use of solid matrices with the CLAM-2030 beyond the current classic liquid ones.
This presentation reports home collection of VAMS samples from patients receiving dasatinib. Duplicate samples were consistent, and preliminary results supported the feasibility of home sampling while confirming substantial variability in trough concentrations.
This presentation examines feasibility of supporting LBA PK analysis using dried blood sample collection technique, with a focus on volumetric absorptive microsampling (VAMS). The result from this feasibility study demonstrates the potential of using a patient-centric sampling procedure for mAb biotherapeutic clinical studies.
This work describes the development of an immunogenicity method using volumetric absorptive microsampling (VAMS® technology), whole human blood and the meso scale Discovery® (MSD®) platform.
This presentation examines comparing volumetric absorptive microsampling (Mitra®) with dried plasma spot for quantification of biazoles in plasma.
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