Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This study developed a sensitive dried-blood assay using Mitra tips to support first-in-human pharmacokinetic evaluation of PF-07059013. Qualification included hematocrit and lot-to-lot testing, with a validated range of 50–50,000 ng/mL.
This study developed and validated a VAMS–LC-MS/MS method for simultaneous measurement of nine biomarkers in mouse whole blood. The simple, robust workflow supported biomarker analysis in drug-discovery studies.
This study developed and validated an ICP-MS/MS method for measuring lead in VAMS whole-blood samples. The results support VAMS as a practical alternative for blood-lead research and potentially other trace-element applications.
This study developed a VAMS–LC-HRMS/MS method to monitor adherence to commonly prescribed antihypertensive drugs. The validated workflow performed consistently across hematocrit levels and supported detection of multiple drug classes from finger-prick blood.
This study used paired whole-blood and plasma data with mixed-effects modeling to support VAMS as the sole pharmacokinetic sampling method in padsevonil trials. The validated model predicted plasma concentrations from blood with a mean bias below 9%.
This study examined how the association between self-reported masking and SARS-CoV-2 infection changed across pandemic phases. While not primarily a microsampling study, it may support COVID-related serology or public health context within the library.
This clinical validation study assessed VAMS for monitoring immunosuppressants and kidney function in transplant recipients. The findings support the feasibility of remote microsampling for therapeutic drug monitoring with appropriate clinical validation.
This presentation evaluates VAMS for tacrolimus measurement in pediatric patients receiving immunosuppressive therapy. The results showed satisfactory agreement with conventional venipuncture-based measurements.
This presentation discusses microsampling to support pharmacokinetic studies and therapeutic drug monitoring in neonatal sepsis. Reduced sample volumes and simplified collection and processing may help personalize antimicrobial dosing in neonates.
Advances in technology and changes to healthcare during the pandemic may finally realize the vision of patient-centric blood testing espoused by disgraced Theranos CEO Elizabeth Holmes.
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