Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This study examines toxic metals in a green transition, with a focus on global health risks, sources, and policy responses-insights from the munich toxic metals symposium 2025. Evidence from mining regions, informal recycling hubs, and urban areas demonstrates widespread and persistent exposure to toxic metals from both legacy and ongoing sources.
This study examines stressing the limits of capillary blood in anti-doping analysis, with a focus on perspectives on alkylamine-like stimulants and carbonic anhydrase II inhibitors in result management. Overall, these findings demonstrate that capillary blood analysis can enhance interpretative context of anti-doping result management, particularly for substances with complex pharmacokinetics, and provide a scientific basis for the future establishment of blood-based reporting criteria.
This study examines respiratory biomarkers, with a focus on an opportunity for patient-centric microsampling approach for treatment optimization. While novel micro-sampling techniques have demonstrated promising results in quantifying drugs and proteins from blood, there is limited exploration within the domain of respiratory diseases' biomarkers.
This study examines reference values for the alcohol biomarker phosphatidylethanol (PEth) in the Belgian population, with a focus on insights from a nationwide microsampling study. These findings provide population-based PEth reference data for Belgium and demonstrate clear differences in PEth distributions between general and higher-exposure populations, supporting improved contextual interpretation of forensic and clinical PEth results.
This dataset supports validation of an HPLC-MS/MS method for cannabinoids and metabolites using volumetric dried blood microsampling. It includes extraction, matrix-effect, calibration, precision, accuracy, hematocrit, stability, selectivity, carryover, and cross-matrix comparison data.
This study examines microsampling for therapeutic drug monitoring and environmental toxicology applications in clinical laboratories. This review summarizes preanalytical, analytical, and quality assurance considerations and offers practical solutions for supporting broader clinical adoption.
This critical review examines emerging mass-spectrometry and sample-preparation strategies for anti-doping analysis. It discusses advanced LC-MS platforms and evolving approaches for screening, confirming, and identifying established and emerging doping agents.
This study evaluates hematocrit-adjusted conversion strategies for mycophenolic acid and tacrolimus monitoring using volumetric absorptive microsampling in lung and renal transplant recipients. Clinical case applications showed that rich eight-point VAMS sampling enabled more accurate AUC estimations than conventional three-point schemes, further highlighting the advantages of using VAMS for MPA TDM.
This conference abstract describes VAMS dried blood microsampling as a potential solution to preanalytical instability in 11-ketotestosterone monitoring for congenital adrenal hyperplasia. It references a validated method for simultaneously quantifying 17-OHP, androstenedione, and 11-KT from a single 20 μL VAMS sample.
This work describes the development and validation of an LC–MS/MS method for the comprehensive quantification of tamoxifen and its metabolites in volumetric absorptive microsampling: clinical application in breast cancer patients. These results demonstrate that the proposed workflow provides a reliable approach for comprehensive tamoxifen metabolite quantification in VAMS samples and supports plasma-equivalent concentration estimation for comparison with existing plasma-based therapeutic data.
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