Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
Researchers developed and validated an LC-MS/MS method for quantifying ivermectin in VAMS samples. The assay met FDA bioanalytical guidance, achieved a 1 ng/mL lower limit of quantification, and was linear across the intended concentration range.
Researchers developed and validated an LC-MS/MS method for measuring warfarin in VAMS samples. The assay met current FDA requirements and was successfully applied to samples from 25 patients receiving warfarin therapy.
Researchers developed and validated a VAMS LC-MS/MS method for measuring cenobamate in patients with refractory epilepsy. The assay was suitable for therapeutic drug monitoring and may support personalized dosing while reducing the burden of repeated venous sampling.
This study assessed dried blood spot methods for detecting recombinant erythropoietin micro-doses, an EPO gene variant, and endogenous EPO in competition samples. Sensitive detection was achieved across Mitra VAMS, Tasso-M20, and filter-paper samples, including cases where matching urine contained no detectable EPO.
This administration study evaluated urine and dried blood spots for detecting a micro-dose of Eporatio® in an anti-doping setting. Dried blood samples remained suspicious for recombinant erythropoietin at later collection times, supporting DBS as an efficient complement to urine testing.
This study compared emergency anti-Xa testing with LC-MS/MS measurement of apixaban and rivaroxaban in plasma and home-collectable VAMS samples. Discordance between methods and matrices showed that laboratories must account for assay differences and measure hematocrit when interpreting VAMS results.
Researchers developed and validated an LC-MS/MS method for measuring endogenous steroid hormones and phase II metabolites in 30 µL VAMS samples for doping-control applications. The analytes remained stable across multiple storage temperatures and freeze–thaw cycles, supporting dried VAMS as a practical matrix for steroid profiling.
Researchers developed and validated LC-MS/MS methods for ciclosporin measurement in whole blood and VAMS samples from pediatric renal-transplant recipients. Both methods met analytical acceptance criteria, supporting VAMS as a less invasive option for therapeutic drug monitoring and potential home collection.
This study used VAMS pharmacokinetic sampling and patient-reported outcomes to identify factors associated with nab-paclitaxel neuropathy in pancreatic cancer. Higher cumulative dose, treatment cycles, and age were associated with more frequent and severe neuropathy.
This study combined surface-enhanced Raman spectroscopy with multivariate analysis to distinguish fibromyalgia from Long COVID using VAMS blood samples. The classification model achieved strong validation performance and identified candidate metabolic spectral biomarkers.
Microsampling and Microbiopsy specialists are available to provide expert support for the success of your project.
