Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This diagnostic-accuracy study compared dental broach, tape disc, and microbiopsy sampling with skin-slit PCR for cutaneous leishmaniasis. Microbiopsy showed lower sensitivity than the other index methods in this study, while the findings also highlighted limitations in the available reference standards.
This feasibility study assessed whether microbiopsy skin samples retain detectable housekeeping-gene RNA under temperatures expected during shipping. Comparable gene detection across storage conditions suggests potential for remote and low-resource workflows, although the small sample set requires further validation.
This perspective explores how digital twins could combine imaging, clinical, molecular, environmental, and patient-generated data in dermatology. It describes potential applications in disease monitoring, prediction, prevention, and personalized intervention while noting the need for validation and responsible data integration.
This thesis reports evaluation of a minimally invasive microbiopsy device for diagnosing cutaneous leishmaniasis in Ethiopia. PCR testing detected more patients than routine skin-slit sampling and was associated with lower pain scores.
This case series followed HIV-infected people with chronic or asymptomatic Leishmania infection in north-west Ethiopia. Persistently high blood parasite levels suggested that both symptomatic and asymptomatic individuals could contribute to transmission, although xenodiagnosis is needed to confirm infectiousness.
This pharmacokinetic study found that patiromer did not meaningfully alter tacrolimus exposure when administered three hours after tacrolimus in kidney transplant recipients. Participants self-collected VAMS samples, demonstrating the method’s suitability for simplifying drug–drug interaction studies.
Researchers validated a UPLC-MS/MS method for measuring Alternaria toxins and their conjugates in urine, capillary blood, and feces. The method demonstrated strong precision, recovery, and sensitivity, while minimally invasive blood microsampling increased its potential for large-scale human biomonitoring.
This review examines VAMS applications in clinical and forensic toxicology, including the measurement of drugs and other substances in blood, urine, and saliva. It highlights improved collection consistency, stability, transport, and patient convenience while noting limitations such as cost and difficulty identifying underfilled samples.
Researchers validated a VAMS–UHPLC-MS/MS method for measuring six oral targeted anticancer agents and their metabolites in dried whole blood. The method met relevant validation requirements, supported room-temperature shipment and long-term frozen storage, and was successfully demonstrated with outpatient samples.
This study developed and clinically validated a Mitra VAMS–LC-MS/MS method for sirolimus in pediatric renal-transplant recipients. The method was equivalent to the reference whole-blood assay and performed reliably across 140 clinical samples without meaningful hematocrit effects.
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