Dive into our dynamic, ever-growing library of peer-reviewed publications, posters, application notes, and presentations showcasing the full breadth and depth of Trajan microsampling technologies. Discover cutting-edge methods, compelling scientific breakthroughs, and real-world applications spanning a wide range of disciplines.
This study validated ear-prick VAMS sampling for iohexol and creatinine measurement in cats. Converted VAMS results agreed closely with venous plasma, supporting a practical, welfare-conscious alternative for estimating glomerular filtration rate.
This study developed a streamlined workflow for proteomic and post-translational modification analysis from 20 µL dried-blood samples. The method quantified thousands of proteins and modified peptides while establishing stability and processing best practices.
This review examines how microsampling is changing pharmacokinetic and toxicokinetic studies in humans and animals. It highlights VAMS as a widely adopted quantitative approach because of its accurate fixed-volume collection and operational flexibility.
This study evaluated Mitra VAMS for trace-element analysis and tested protocols to reduce background contamination. Rigorous tip cleaning improved detection performance while clarifying the method’s strengths and remaining limitations for environmental-health research.
This review examines patient-centric microsampling for therapeutic drug monitoring of immunosuppressants. The approaches may improve individualized dosing and post-transplant care while reducing burdens associated with conventional venous sampling.
This review compares microsampling approaches with conventional blood matrices for metabolic biomarker analysis. It outlines analytical performance considerations and critical steps for integrating microsamples into biomarker discovery and clinical diagnostics.
This study combined VAMS with electromembrane extraction to measure doxorubicin and its metabolite in whole blood. The optimized approach reduced matrix effects, improved throughput, and was successfully applied to samples from treated mice.
This study developed an LC-MS/MS workflow to quantify three therapeutic monoclonal antibodies from VAMS blood samples. Measured concentrations fell within expected therapeutic ranges, supporting the method’s potential for less-invasive therapeutic drug monitoring.
This study compared the analytical and usability performance of four dried-blood devices for glucocorticoid detection in sports testing. Performance varied by format, and the findings support further validation before routine anti-doping implementation.
This study combined oral-fluid VAMS with UHPLC-HRMS to quantify cannabinoids and metabolites from 20 µL samples. Application to samples from cannabis users demonstrated sensitive measurement across a broad concentration range.
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