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microsampling for research

Research Data
Visit our library of published studies and other resource materials for data-driven information.
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Read about which analytes can & cannot be measured in dried blood microsamples.
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Frequently Asked Questions (FAQs)

Have your microsampling devices with volumetric technology been used in real-world research studies?

Yes, our microsampling devices with volumetric technology have been used in research studies around the world. Our Technical Resource Library includes a searchable selection of published literature discussing research studies and trials with both adult and pediatric study participants applying remote specimen collection and volumetric microsampling. Type your analyte of interest in the library's search field to find journal articles, presentations and application notes from third-party research groups.

Which analytes have been extracted and validated using volumetric microsampling?

Many analytes can be extracted using volumetric microsampling, and are compatible with hemaPEN® and Mitra® devices with VAMS® technology. Our Technical Resource Library provides information around the types of analytes that have been evaluated by researchers using volumetric microsampling. Type your analyte of interest in our Technical Resource Library search field to find the information you seek. 

What are the sample success rates for remote microsampling devices?

Sample success rates are high for Mitra® and hemaPEN® devices, which are based on volumetric microsampling. The absorptive VAMS® tips on Mitra can absorb homogenous samples with 99% acceptance rates. By following the illustrated instructions and demo videos available with hemaPEN and Mitra, end-users can reliably collect fixed volume samples that are precise enough for lab analysis.

These volumetric microsampling devices overcome the hematocrit (HCT) bias that may occur with DBS cards, where non-homogenous blood spots on filter paper have higher variability and higher failure rates.

How does dried capillary blood compare to other blood sources?

Published research papers show that dried capillary whole blood microsamples collected in 10, 20, or 30 µL volumes are enough for good extraction and analysis. These samples also yield high-quality data that are similar to data from venous blood. The literature provides case examples of microsampling in research applications. Visit the Technical Resource Library to review many comparative studies that describe what others have achieved with microsampling in their research.

How long will it take to implement microsampling technology?
The process of transitioning to microsampling takes about 6-8 months and is divided into three phases, with ongoing technical support from the Neoteryx Microsampling Team:
Education: [1 - 2 weeks] The introductory phase 
Evaluation: [4 - 6 weeks] Extraction, linearity & signal-to-noise studies
Validation: [6 - 8 months] Validating your method

See our Microsampling User Guide for details.
What is the cost comparison between dried blood microsampling vs. conventional venous blood sampling?

Dried blood sampling (e.g., using Mitra® devices, hemaPEN® devices or DBS cards) eliminates the requirement & expense of a certified phlebotomist to perform the blood sample collection. In addition, the shipping of dried blood samples to a central laboratory doesn’t require costly cold-chain shipping supplies/methods, but instead can be shipped via standard post.

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Which analytes can you extract from dried blood microsamples?

To find out, download our List of Compatible Analytes!

Analytes Compatible with Microsampling

Specific proteins, vitamins, minerals, heavy metals, hormones and other analytes are included in our list. Fill out the form to download the PDF and as a bonus you will also gain access to our technical resource library of published journal articles and resources from your peers who are leveraging microsampling.

Complete Form to Download

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