extract high-quality RNA even after 7 days of storage
simplify RNA collection with GenTegraRNA-NEO
stabilize RNA in ambient conditions
high-quality RNA from dried blood microsamples
The Mitra® microsampling device, based on the industry's leading Volumetric Absorptive Microsampling (VAMS®) technology, paired with GenTegraRNA-NEO's cutting-edge RNA stabilization technology, facilitates the collection of high-quality RNA samples without the need for cold-chain logistics.
unlock the full potential of your RNA research
GenTegraRNA-NEO introduces a dynamic RNA stabilization solution tailored for use with VAMS® Microsampling technology. This Active Chemical Protection™ formula ensures RNA integrity by shielding against environmental stressors and nucleases, making it ideal for remote and decentralized research environments. Without the need for cold storage / logistics, it facilitates the collection of high-quality RNA samples from broad populations, simplifying workflows and reducing operational costs.
Protection
GenTegraRNA-NEO shields RNA from degradation, ensuring sample integrity during storage and transport.
Ease of Use
Mitra VAMS tips treated with GenTegraRNA-NEO are compatible with finger-stick blood collection and can be used by virtually anyone, anywhere
Stabilization
Offers up to 7 days of RNA preservation over a range of temperatures and humidity's.
Cost Effective
Advance your RNA research with greater access to diverse, decentralized populations, reduced need for trained clinical staff, and reduced specimen handling costs.
suitable research application areas
GenTegraRNA-NEO
The GenTegraRNA-NEO solution is an Active Chemical Protection™ (ACP) technology by GenTegra distributed by Trajan for use on Mitra® devices based on VAMS® technology. You can use GenTegraRNA-NEO to pre-treat the Mitra devices and advance the way you collect, protect, and process your RNA samples. The GenTegraRNA-NEO comes as a dried matrix that you easily rehydrate in the lab. The rehydrated solution can be coated onto and dried on the VAMS tips of Mitra devices. When a sample is collected onto the VAMS tips GenTegraRNA-NEO will block naturally occurring nucleases and protect against environmental stresses.
Key features:
- Advanced RNA stabilization with the Active Chemical Protection™ (ACP) technology by GenTegra
- Dry matrix format for long term storage at room temperature
- Optimized volume to treat 32 VAMS tips (30µL)
Indication for use: For Research Use Only
Catalog Number: GTRNEO-32
Content: 1x Dried matrix in 2mL vial in ziplock bag
Shelf-Life as Dried Matrix: 3-years at room temperature
Shelf-Life as Rehydrated Solution: 6 months at 4°C rehydrated in water
Suitable VAMS Tip: 30μL
# tip to be treated per vial: 32 VAMS tips
RNA Stabilization in Whole Blood: 7 days – dried whole blood on VAMS tip at room temperature
RNA Yield: Up to 200ng per 2x 30μL VAMS tips (depends on extraction methodology & amount of RNA in sample)
RNA Quality: Typical RIN Scores > 6 (@ 7 days, room temperature, dry conditions)
Promega Provides App Note for Automated RNA Purification on Trajan Microsampling Devices for RNA-based Studies
Researchers at Promega have published an application note demonstrating a method for purifying Total RNA, including miRNA, from whole blood collected on the VAMS® tips of Trajan’s Neoteryx Mitra® devices treated with GenTegraRNA-NEO™ solution using the Promega Maxwell® RSC simplyRNA Blood Kit and Maxwell® RSC Instrument.
Cellecta Researchers Profile RNA Biomarkers in Dried Blood Microsamples
Using Mitra® microsampling devices that were pre-treated with GenTegraRNA-NEO for RNA stabilization before blood collection, Cellecta researchers analyzed the samples with the DriverMap™ Targeted RNA-Seq Expression Profiling Technology 19K Panel and the DriverMap™ T/B Immune Marker Panel to effectively detect up- and down-regulated genes in blood microsamples.
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