Substance-abusing employees can detrimentally impact a company's productivity and bottom line. Data from the National Safety Council paints a stark picture:
Given these concerns, numerous corporate entities have introduced drug-testing protocols to identify and manage substance abuse among employees. The types of tests are shaped by various determinants, including regional and federal regulations and the specific substances being screened.
The longevity of a drug's detectable presence in the human body varies considerably. For example, the euphoric effects of cocaine might last merely 15-30 minutes, but the drug can persist in a person's system much longer.
Similarly, LSD's psychoactive impact in the system lasts 6-12 hours. Alcohol's dynamics are more multifaceted: post-consumption, it can be identified in a person's breath and blood for nearly a day. Alcohol can be traced in urine for upwards of 80 hours.
The strategy for analyzing biological samples to screen for drugs and alcohol correlates to how long a substance remains in the system. While certain drugs fade rapidly, others linger for extended periods.
Factors influencing a drug's stay in the human body include:
The drug or alcohol tests performed by a toxicology lab or other laboratory may vary depending on the type of substance or drug being screened, and the types of samples needed for lab analysis. The most common drug test types include:
However, urine samples are less effective than some other methods at detecting drugs and alcohol because they have a short retrospective period. In other words, a urine test is less likely to detect regular drug use beyond a 48-window period. Another drawback of urine testing is the ease and opportunity for tampering with or switching out the samples.
While whole blood testing is more invasive than breath tests and urine tests, it’s the most effective at detecting specific alcohol concentration levels in a person's system. Certain blood tests show the precise levels of intoxication 24 hours after drinking.
The microsamples from these devices can be analyzed in the lab following a typical dried blood spot (DBS) workflow. Blood can reveal more than just the presence of drugs. researchers have discovered that PEth, a direct biomarker of alcohol consumption, can be detected in blood microsamples. Bioanalysis of blood microsamples also shows drug metabolites in the blood, and the actual level of drugs in the blood.
In summary, to maintain safety and compliance across different sectors, it's crucial to understand common drug and alcohol testing methods. Each method offers unique advantages and limitations, and selecting the appropriate test depends on the specific context and objectives.