A microsampling pioneer in Italy has recently developed, validated, and submitted for publication a new LC-MS/MS method for measuring concentrations of a range of antiepileptic drugs (AEDs) using Volumetric Absorptive Microsampling (VAMS™) technology. Dr. Ugo de Grazia and his collaborators at Fondazione IRCCS Istituto Neurologico Carlo Besta Neurological Hospital in Milano have established a useful example for facilitating easier antiepileptic drug monitoring and for dealing extraction difficulties of small drugs on different physical-chemical properties.
Patient monitoring is always an important part of the medical process, but it’s particularly crucial when patients are using drugs with a narrow therapeutic index. Drugs with a narrow therapeutic index are drugs in which the dosage must be exact; otherwise, it could lead to serious negative reactions, failures, or dependency. Regular therapeutic drug monitoring is very important for patients taking these drugs.
There are many cases in which it is necessary to test people for alcohol consumption, including organ transplants, driver’s license regranting, and more. Traditional testing methods involving hair or urine have obvious and subtle drawbacks, and traditional alcohol biomarkers can't always be used to make finer distinctions between teetotalers, social drinkers, and heavy drinkers or alcoholics.
Over the past few years, the field of medicine has witnessed advancements that have brought new convenience, comfort, and efficiency to patient treatment. One of these is microsampling.
The rise of blood microsampling technology has dramatically simplified the process of blood collection. In many cases, it is no longer necessary to undergo painful venipuncture, to involve phlebotomists and complex lab equipment, or to use dry ice and biohazard shipping to get the blood sample safely to the clinic. Now, instead, there’s finger-prick / finger-stick sampling.
With a microsampling device, a very small sample of blood can be collected from a patient anywhere in the world. It works just with a single finger prick and collects just a few microliters of blood. Microsampling has dramatic positive implications for the science and healthcare fields because it makes healthcare smarter and research and patient monitoring much easier. Here are some of the ways that microsampling is changing the world.