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what lab managers should know about immunosuppressant monitoring

Posted by Neoteryx on Jan 23, 2020 1:23:00 AM

When using immunosuppressant drugs as an organ transplant recipient, it is crucial to effectively and consistently monitor drug levels. This requires therapeutic drug monitoring and an understanding of requirements and best practices for therapeutic drug monitoring in the laboratory.

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Topics: Immunosuppressants

immunosuppressant drug monitoring: research supports microsampling

Posted by Neoteryx on Jan 14, 2020 4:43:00 AM

Therapeutic drug monitoring (TDM) for immunosuppressive drugs (ISPs) is a critical component of post-tissue and organ transplantation therapy. This is because ISP drugs have high intra- and inter-subject variability and a narrow therapeutic window. Initially, quantitative analyses of ISPs such as sirolimus, cyclosporine A, tacrolimus, and everolimus used whole blood specimens.

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Topics: Alternative to Dried Blood Spot, Alternative to Venipuncture, Immunosuppressants

therapeutic drug monitoring of immunosuppressants: an overview

Posted by Neoteryx on Jan 6, 2020 2:52:00 AM

When administering immunosuppressants, clinicians need to individualize a patient’s drug therapy. The goal is to attain an optimal balance between therapeutic efficacy and the probability of adverse effects. Patients present varying pharmacodynamics and pharmacokinetics, so achieving this goal can be challenging.

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Topics: Alternative to Dried Blood Spot, Alternative to Venipuncture, Immunosuppressants

smarter, simpler immunosuppressant monitoring: the promise of capillary blood microsampling innovation

Posted by Neoteryx on Dec 17, 2019 4:04:00 AM

For many organ transplant patients, immunosuppressant monitoring is a fact of life. But that does not mean that it cannot be significantly improved. For proof, look no further than the remote blood sampling capabilities provided by Mitra® microsampling devices, driven by Volumetric Absorptive Microsampling (VAMS®) technology.

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Topics: Immunosuppressants

patient-centered auc-monitoring for tacrolimus: encouraging news from norway

Posted by Neoteryx on Jul 11, 2019 7:11:00 AM

At the 2019 meeting of the American Transplant Congress, held this year in Boston, scientists from the Oslo University Hospital, Rikshospitalet presented exciting findings regarding more patient-centered AUC-monitoring of tacrolimus, a cornerstone immunosppressant, using blood microsampling systems driven by Mitra® devices and Volumetric Absorptive Microsampling (VAMS™) technology. Researcher and PhD student Marte Theie Gustavsen was on hand to give the presentation and made time to answer a few questions.

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Topics: Alternative to Venipuncture, Remote Patient Monitoring, Immunosuppressants

how capillary blood microsampling facilitates patient-centered tacrolimus monitoring

Posted by Neoteryx on Jul 9, 2019 7:09:00 AM

Capillary blood microsampling is a technique that has made collection and analysis of small, exact volumes of liquid matrices much simpler. Through capillary blood microsampling, tacrolimus monitoring has potentially become more patient-centered. Here's why you should consider blood microsampling when it comes to tacrolimus monitoring.

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Topics: Remote Patient Monitoring, Immunosuppressants